Laboratory of Exercise Biochemistry in Health
Ricardo Pinho´s Lab
Lab overview
Bioex is linked to the Graduate Program in Health Sciences (PPGCS) of the School of Medicine at the Pontifical Catholic University of Paraná (PUCPR) in Brazil. Our research aims to understand the biochemical and molecular mechanisms induced by physical exercise on the redox biology in diverse tissues and organs. We use advanced technologies and research techniques to explore and investigate the scientific hypotheses formulated in our Laboratory. Our research is supported by government funding and other foundations.
OUR TEAM
The Bioex team is composed of researchers, undergraduate and postgraduate students (master's and doctorate), post-doc and collaborators. Know more about the members of our team below.
Head of Lab and main investigator
Ricardo A. Pinho, PhD
Dr. Pinho has an undergraduate and a Master's degree in Physical Education (UFSC, Brazil,1992/1999) and a Ph.D. in Biological Sciences - Biochemistry (UFRGS, Brazil, 2005). Senior postdoctorate at the Muscle Health Research Centre - YU - Toronto. Dr. Pinho was the Director of Community Affairs, Coordinator for Graduate Studies and Research in Health Science, and Pro-rector for Graduate Studies and Research at Universidade do Extremo Sul Catarinense. Currently, Dr. Pinho is a professor of Graduate and undergraduate programs at the School of Medicine at Pontificia Universidade Católica do Paraná (PUCPR), Brazil. In the Graduate Program in Health Sciences, Dr. Pinho is a professor and supervisor (MSc and Ph.D.) and Head of the Biochemistry of Exercise Lab in Health. He is a member of the Society for Free Radical Research - Europe and a Member of the Advisory Board in the Area of Biological Sciences of the Araucária Foundation (Paraná, Brazil). Acts as a reviewer for several international journals and is Associate Editor of The Annals of the Brazilian Academy of Science. Dr. Pinho has experience in the Biochemistry and physiology of exercise, mainly oxidative stress and pathophysiology of chronic degenerative diseases. (CNPQ scientist , index-h = 34 ISI, 33 Scopus, 46 Google Scholar).
PROJECTS IN PROGRESS
Our projects aim to investigate the role of physical exercise and antioxidants on the redox response of degenerative diseases. Research in the BIOEX involves a constant review of the scientific issues on exercise and health.The strength of our research lies in the breadth and depth of the experimental approaches we use in understanding the molecular and biochemical mechanisms induced by physical exercise. Learn more about our current research projects below.
Regulation of resistance physical exercise on oxidative stress parameters and genetic variations in different stages of sarcopenia
Resistance Exercise Modulates Oxidative Stress Parameters and TNF-α Content in the Heart of Mice with Diet-Induced Obesity.
Arq Bras Cardiol. 2019 May;112(5):545-552.
Effects of chronic treatment with gold nanoparticles on inflammatory responses and oxidative stress in Mdx mice.
J Drug Target. 2019 Jun 27:1-9.
Cardioprotective effects of physical exercise on redox biology in mice exposed to hand-rolled cornhusk cigarette smoke.
Arch Biochem Biophys. 2019 Jan;661:50-55.
Swimming training improves mental health parameters, cognition and motor coordination in children with Attention Deficit Hyperactivity Disorder.
Int J Environ Health Res. 2019 May 13:1-9.
Effects of aquatic exercise on mental health, functional autonomy and oxidative stress in depressed elderly individuals: A randomized clinical trial.
Improvement in muscular strength and aerobic capacities in elderly people occurs independently of physical training type or exercise model.
Effects of photobiomodulation on mitochondria of brain, muscle, and C6 astroglioma cells.
Med Eng Phys. 2019 Sep;71:108-113.
Therapeutic effects of iontophoresis with gold nanoparticles in the repair of traumatic muscle injury.
J Drug Target. 2019 Aug 16:1-13.
Effects Of Treatment With Gold Nanoparticles In A Model Of Acute Pulmonary Inflammation Induced By Lipopolysaccharide.
Cardio-respiratory health effects of exposure to traffic-related air pollutants while exercising outdoors: A systematic review.
Environ Res. 2019 Aug 16;178:108647.
Effects of chronic treatment with gold nanoparticles on inflammatory responses and oxidative stress in Mdx mice.
J Drug Target. 2019 May 3:1-27.
Effects of Resistance Exercise on Cerebral Redox Regulation and Cognition: An Interplay Between Muscle and Brain
Antioxidants (Basel). 2019 Nov 6;8(11)
RECENT PUBLICATIONS
The results of our research are published in different international journals, which have been cited and recognized by other researchers. See some of our recent publications (2019/2021). You can find a complete list of our publications at https://publons.com/researcher/G-2643-2012/
Exercise, redox system and neurodegenerative diseases
Physical exercise: An inducer of positive oxidative stress in skeletal muscle aging
Yerba mate (Ilex paraguariensis St. Hil.) extract inhibits hand-rolled cornhusk cigarette smoke-induced oxidative pulmonary damage
Susceptibility of the patients infected with Sars-Cov2 to oxidative stress and possible interplay with severity of the disease
Effect of taurine associated gold nanoparticles on oxidative stress in muscle of mice exposed to overuse model
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Effect of taurine associated gold nanoparticles on oxidative stress in muscle of mice exposed to overuse model
Lab Symposium
Symposium of Exercise Biochemistry in Health
The Symposium of Exercise Biochemistry in Health is an event promoted by Bioex to disseminate scientific advances related to physical exercise's biochemical and molecular effects on human health. The event is held annually at PUCPR and has the participation of important researchers. In 2021 the event was held online on the 23rd, 24th, and 25th of June.
Website: https://bioex.pucpr.br
A little of our scientific and social routine
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Contact us
Thank you for your interest in our research. Please contact us if you have any questions or comments about our work and publications, or, if you wish to try out for a master´s degree, doctorate or a post-doc position. We would love to hear from you.
Adress: R. Imac. Conceição, 1155 - Prado Velho, Curitiba - PR, 80215-901, Brazil
e-mail: bioex.pucpr@gmail.com
Phone: (+55 48) 32716333